TABLE V.
Power of the proposed test statistics for Case 3 and IM2 with the interaction β = 2, for different sizes of the blocks (p1 and p2) and different amounts of LD within the block (measured using |CLD| = |r|). For this set of simulations, 1000 cases and 1000 controls were sampled for each of 1000 simulation runs. We completed 10000 permutations for each data set, and controlled the significance level at α = 0.05.
| CLD | ||||||||
|---|---|---|---|---|---|---|---|---|
| 0.2 | 0.3 | 0.4 | 0.5 | 0.6 | 0.7 | 0.8 | ||
| p1 = p2 = 4 | δ2 | 0.303 | 0.321 | 0.364 | 0.425 | 0.481 | 0.291 | 0.211 |
| LM1 | 0.175 | 0.186 | 0.204 | 0.212 | 0.228 | 0.240 | 0.181 | |
| LM2 | 0.184 | 0.205 | 0.211 | 0.228 | 0.249 | 0.251 | 0.190 | |
| p1 = p2 = 6 | δ2 | 0.349 | 0.381 | 0.405 | 0.483 | 0.511 | 0.544 | 0.460 |
| LM1 | 0.146 | 0.153 | 0.158 | 0.165 | 0.180 | 0.198 | 0.163 | |
| LM2 | 0.151 | 0.163 | 0.169 | 0.188 | 0.195 | 0.213 | 0.186 | |
| p1 = p2 = 20 | δ2 | 0.381 | 0.431 | 0.485 | 0.558 | |||
| LM1 | 0.091 | 0.108 | 0.114 | 0.121 | ||||
| LM2 | 0.096 | 0.115 | 0.120 | 0.125 | ||||