Skip to main content
. Author manuscript; available in PMC: 2013 Sep 1.
Published in final edited form as: Genet Epidemiol. 2012 Jul 10;36(6):622–630. doi: 10.1002/gepi.21656

TABLE V.

Power of the proposed test statistics for Case 3 and IM2 with the interaction β = 2, for different sizes of the blocks (p1 and p2) and different amounts of LD within the block (measured using |CLD| = |r|). For this set of simulations, 1000 cases and 1000 controls were sampled for each of 1000 simulation runs. We completed 10000 permutations for each data set, and controlled the significance level at α = 0.05.

CLD

0.2 0.3 0.4 0.5 0.6 0.7 0.8
p1 = p2 = 4 δ2 0.303 0.321 0.364 0.425 0.481 0.291 0.211
LM1 0.175 0.186 0.204 0.212 0.228 0.240 0.181
LM2 0.184 0.205 0.211 0.228 0.249 0.251 0.190

p1 = p2 = 6 δ2 0.349 0.381 0.405 0.483 0.511 0.544 0.460
LM1 0.146 0.153 0.158 0.165 0.180 0.198 0.163
LM2 0.151 0.163 0.169 0.188 0.195 0.213 0.186

p1 = p2 = 20 δ2 0.381 0.431 0.485 0.558
LM1 0.091 0.108 0.114 0.121
LM2 0.096 0.115 0.120 0.125