Table 1. Lethality results.
| Phase | Dosage Group | No. of Animals | Target Challenge Dosage (cfu/animal) | Calculated Inhaled Dosage (cfu/animal) | No. of Animals Died |
|---|---|---|---|---|---|
| I | I-A | 6 | 5 | 7 | 0 |
| I-B | 6 | 10 | 9 | 0 | |
| I-C | 6 | 25 | 5 | 0 | |
| I-D | 6 | 50 | 58 | 0 | |
| I-E | 6 | 100 | 27 | 0 | |
| I-F | 5 | 500 | 122 | 0 | |
| I-G | 6 | 1,000 | 1,068 | 2 | |
| I-H | 6 | 5,000 | 5,854 | 2 | |
| II | II-A | 6 | 7,000 | 8,910 | 6 |
| II-B | 6 | 8,000 | 12,408 | 6 | |
| II-C | 6 | 10,000 | 9,966 | 6 | |
| II-D | 5 | 25,000 | 28,896 | 5 | |
| II-E | 6 | 50,000 | 54,824 | 6 | |
| II-F | 6 | 100,000 | 106,260 | 6 | |
| III | III-A | 6 | 2,000 | 3,309 | 2 |
| III-B | 6 | 3,000 | 4,488 | 5 | |
| III-C | 6 | 4,000 | 6,798 | 6 | |
| III-D | 6 | 5,000 | 9,725 | 5 | |
| III-E | 6 | 7,000 | 11,286 | 6 | |
| III-F | 6 | 8,000 | 14,424 | 6 |