Figure 4. Effects of 4-PBA on the differential cellular components (a), plasma exudation using EBD assay (b), total protein amounts (c) in BAL fluids, and pathologic and radiologic changes (d) of LPS-treated mice.

All parameters were measured at 48 hours after LPS treatment in 0.9% NaCl solution (saline)-treated mice administered with drug vehicle (PBS) (SAL+PBS), LPS-treated mice administered with PBS (LPS+PBS), or LPS-treated mice administered with 4-PBA (LPS+PBA). Bars represent mean ± SEM from 8 mice per group in (a-c). ^#P < 0.05 versus SAL+PBS; ^*P < 0.05 versus LPS+PBS. (d) Representative H&E stained sections of the lungs isolated from SAL+PBS, LPS+PBS, and LPS+PBA. Bars indicate 50 μm. As for the micro-CT scan images, representative transaxial images (the upper panels) and coronal images (the bottom panels).