Table 1.
Statistical uncertainty of predicted and observed ICs [means (95% CIs)] for mixtures.
| Inhibition level x | Inhibition concentration ICX(mixture) [M] | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Observed | Predicted by CA | Predicted by IA | ||||||||||
| 8 pesticides (IC01)a | ||||||||||||
| 10% | 1.65E-6 | (1.11E-6, 2.21E-6) | 2.12E-6 | (1.87E-6, 2.29E-6) | 5.47E-6 | (4.10E-6, 6.18E-6)* | ||||||
| 50% | 9.74E-6 | (7.91E-6, 1.07E-5) | 9.66E-6 | (9.00E-6, 1.03E-5) | 1.35E-5 | (1.20E-5, 1.46E-5)* | ||||||
| 8 pesticides (IC10)a | ||||||||||||
| 10% | 1.49E-6 | (1.23E-6, 1.85E-6) | 1.87E-6 | (1.64E-6, 2.03E-6) | 4.57E-6 | (3.46E-6, 5.26E-6)* | ||||||
| 50% | 8.79E-6 | (7.55E-6, 1.04E-5) | 9.13E-6 | (8.53E-6, 9.76E-6) | 1.32E-5 | (1.17E-5, 1.45E-5)* | ||||||
| 5 pesticides (IC01)a | ||||||||||||
| 10% | 1.03E-5 | (8.25E-6, 1.21E-5) | 6.73E-6 | (5.86E-6, 7.82E-6)* | 1.39E-5 | (1.13E-5, 1.66E-5) | ||||||
| 50% | 3.35E-5 | (2.95E-5, 3.78E-5) | 2.80E-5 | (2.58E-5, 3.09E-5) | 3.60E-5 | (3.28E-5, 4.10E-5) | ||||||
| 5 pesticides (IC10)a | ||||||||||||
| 10% | 8.97E-6 | (6.77E-6, 1.20E-5) | 6.38E-6 | (5.47E-6, 7.28E-6) | 1.33E-5 | (9.93E-6, 1.67E-5) | ||||||
| 50% | 3.54E-5 | (3.11E-5, 4.06E-5) | 2.89E-5 | (2.68E-5, 3.19E-5) | 3.77E-5 | (3.41E-5, 4.32E-5) | ||||||
| 13 pesticides (IC01)a | ||||||||||||
| 10% | 5.56E-6 | (4.38E-6, 7.39E-6) | 3.89E-6 | (3.55E-6, 4.16E-6)* | 1.38E-5 | (1.06E-5, 1.52E-5)* | ||||||
| 50% | 2.61E-5 | (2.38E-5, 2.95E-5) | 1.70E-5 | (1.61E-5, 1.80E-5)* | 3.11E-5 | (2.83E-5, 3.37E-5) | ||||||
| 13 pesticides (IC10)a | ||||||||||||
| 10% | 5.20E-6 | (3.47E-6, 7.28E-6) | 3.61E-6 | (3.24E-6, 3.88E-6) | 1.11E-5 | (8.24E-6, 1.27E-5)* | ||||||
| 50% | 2.86E-5 | (2.68E-5, 3.01E-5) | 1.71E-5 | (1.63E-5, 1.80E-5)* | 3.14E-5 | (2.81E-5, 2.81E-5) | ||||||
| 13 pesticides (IC20)a | ||||||||||||
| 10% | 3.25E-6 | (2.28E-6, 4.91E-6) | 3.48E-6 | (3.14E-6, 3.75E-6) | 1.01E-5 | (7.30E-6, 1.17E-5)* | ||||||
| 50% | 2.42E-5 | (2.09E-5, 2.89E-5) | 1.71E-5 | (1.63E-5, 1.80E-5)* | 3.06E-5 | (2.72E-5, 3.35E-5) | ||||||
| 13 pesticides (IC50)a | ||||||||||||
| 10% | 5.41E-6 | (3.70E-6, 7.44E-6) | 3.35E-6 | (2.99E-6, 3.64E-6)* | 9.14E-6 | (6.47E-6, 1.08E-5) | ||||||
| 50% | 3.24E-5 | (2.70E-5, 3.67E-5) | 1.75E-5 | (1.65E-5, 1.85E-5)* | 2.89E-5 | (2.57E-5, 3.20E-5) | ||||||
| aSee Supplemental Material, Table S1 (http://dx.doi.org/10.1289/ehp.1205391) for mixture ratios. *Statistically significant compared with observed ICs. Significance between predicted and observed ICX values was judged as a non-overlapping of their 95% percentile bootstrap CIs. | ||||||||||||