Table 6.

Significance of survival association for GNS signature and IDH1 status

		Single covariate		Two covariates
Data set	Number of cases	GNS signature	IDH1 status	GNS signature	IDH1 status
TCGA	270	5.3 × 10-5	0.0015	0.0091	0.1489
Gravendeel, glioblastoma cases	118	2.7 × 10-5	0.0031	9.2 × 10-4	0.0840
Gravendeel, grade I to III glioma cases	86	6.5 × 10-4	0.5776	6.3 × 10-4	0.5408

Wald test P-values, indicating association with survival, for each covariate in a Cox proportional hazards model with one or two covariates (GNS signature, IDH1 status or both). Cases with unknown IDH1 mutation status were excluded.