Table 3.
Peripheral blood changes observed in rats after 82 days treatment with different doses of C. edulis CH2Cl2/MeOH (1:1) stem bark extract.
Sex of animal | Dose (mg/kg BW) | Hematocrit (%) | WBC counts (x10 3 /mm 3 ) | RBC counts (x10 6 /mm 3 ) |
---|---|---|---|---|
Females | 0 | 49.41±1.93a | 5.32±0.68a | 4.25±0.32a |
25 | 48.28±2.32a | 5.40±0.93a | 4.10±0.61a | |
50 | 47.07±2.63a | 6.16±0.64a | 3.96±0.52a | |
100 | 47.61±1.47a | 5.40±0.59a | 3.71±0,29a | |
200 | 46.09±1.81a | 5.20±0.82a | 3.66±0.33a | |
Males | 0 | 48.64±1.26a | 5.84±1.13a | 4.14±0.32a |
25 | 50.42±1.84a | 5.32±0.38a | 4.46±0.60a | |
50 | 47.04±1.35ab | 5.68±0.61a | 3.86±0.39a | |
100 | 46.83±1.77ab | 5.48±0.69a | 3.73±0.47a | |
200 | 45.06±1.24b | 4.92±0.33a | 3.64±0.57a |
Values are expressed as mean±SD of five animals. Doses are expressed in mg/kg body weight (BW), WBC: white blood cells; RBC: red blood cells. For the same sex and in the same column, values bearing different superscript letters are significantly (p < 0.05) different from each other.