Table 4.
Study | Surgery | Size (cm) | CND (%) | Operative time (min) | Complications (%) | ||||
---|---|---|---|---|---|---|---|---|---|
Transient hypocalcemia | Permanent hypocalcemia | Transient RLN palsy | Permanent RLN palsy | Hematoma | |||||
Jong et al. [10] | O (n = 224) E (n = 275) |
O: 0.60 ± 0.22 E: 0.56 ± 0.19 |
Prophylactic ipsilateral in all patients | O: 105.5 ± 41.6 E: 138.5 ± 49.0 |
O: 17.1 E: 31.0 |
O: 1.7 E: 0.0 |
O: 2.2 E: 5.5 |
O: 0.4 E: 0.4 |
O: 0.9 E: 1.5 |
| |||||||||
Di et al. [11] | O (n = 37) E (n = 31) |
O: 0.73 ± 0.14 E: 0.76 ± 0.15 |
All patients underwent CND | O: 105.4 ± 37.0 E: 143.9 ± 19.2 |
O: 2.7 E: 9.7 |
O: 0.0 E: 0.0 |
O: 5.4 E: 9.7 |
O: 0.0 E: 0.0 |
O: 0.0 E: 0.0 |
| |||||||||
Kim et al. [12] | O (n = 138) E (n = 95) R (n = 69) |
O: 0.7 ± 0.2 E: 0.6 ± 0.2 R: 0.6 ± 0.2 |
Prophylactic ipsilateral in all patients | O: 81 ± 16 E: 136 ± 31 R: 196 ± 45 |
O: 27.5 E: 25.3 R: 33.3 |
O: 0.0 E: 2.1 R: 0.0 |
O: 0.7 E: 2.1 R: 1.4 |
O: 0.0 E: 2.1 R: 0.0 |
O: 0.0 E: 1.1 R: 0.0 |
| |||||||||
Lee et al. [13] | E (n = 96) R (n = 163) |
E: 0.84 ± 0.41 R: 0.87± 0.64 |
E: 54.2 R: 91.4 |
E: 142.7 ± 52.1 R: 110.1 ± 50.7 |
E: 0.0 R: 12.5 |
E: 0.0 R: 0.0 |
E: 3.1 R: 1.8 |
E: 1.0 R: 0.6 |
E: 3.1 R: 0.6 |
| |||||||||
Chung et al. [14] | O (n = 198) E (n = 103) |
≤0.5 cm (%) O: 52.0 E: 56.3 0.5–1 cm (%) O: 48.0 E: 43.7 |
O: 8.1 E: 1.0 |
O: 111.4 E: 165.1 (S.D. not reported) |
O: 17.7 E: 25.2 |
O: 4.5 E: 1.0 |
O: 2.5 E: 25.2 |
O: 0.5 E: 0.0 |
O: 0.0 E: 1.0 |
O: open thyroidectomy, E: endoscopic thyroidectomy, R: robot assisted thyroidectomy, CND: central lymph node dissection, S.D.: standard deviation, continuous variable reported as mean ± S.D., categorical variables reported as percentages (%).