Table 2.

Relationships of the Loci ATF7IP at 12p13 and KLK2 at 19q13 with tPSA Levels.

Locus	SNP (Minor Allele)	REDUCE (N = 3192)			CAPS (N = 464)			Pcombined*
		Mean†	β	P‡	Mean†	β	P‡
12p13 (ATF7IP)	rs3213764 (G)	6.00/5.86/5.81	-0.015	0.069	4.88/4.41/4.37	-0.053	0.027	0.015
19q13 (KLK2)	rs1354774 (G)	5.89/5.85/6.00	0.002	0.846	4.58/4.49/4.31	-0.024	0.342	0.904

^*Pcombined values were estimated using inverse variance-weighted meta-analyses according to regression coefficients (β) and corresponding SEs across studies.

^†Mean values of tPSA (%) by genotypes (major homozygote/heterozygote/minor homozygote).

^‡P values were from linear regression models adjusted for age.