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. 2013 Jan;15(1):95–101. doi: 10.1593/neo.121620

Table 3.

Relationships of the Loci ATF7IP at 12p13 and KLK2 at 19q13 with Prostate Cancer Risk (Case-Control Study) or Aggressiveness (Case-Only Study).

Locus SNP (Minor Allele) Case-Control Study Case-Only Study


MAFcase/control OR (95% CI)* P* MAFagg/nonagg OR (95% CI)* P*


REDUCE (N = 410/1234) CAPS (N = 2899/1722) REDUCE (N = 124/281) CAPS (N = 1231/1619)
ATF7IP rs3213764 (G) 0.445/0.465 0.519/0.499 1.05 (0.97–1.13) 0.214 0.456/0.441 0.524/0.517 1.02 (0.92.1.13) 0.737
KLK2 rs1354774 (G) 0.345/0.341 0.340/0.335 1.01 (0.94–1.10) 0.722 0.367/0.336 0.332/0.344 0.98 (0.88.1.09) 0.716
*

Odds ratios (ORs), 95% confidence intervals (CIs), and P values were estimated using inverse variance-weighted meta-analyses according to regression coefficients and corresponding SEs across REDUCE and CAPS studies.