Table 5.
Institution/Author | n | Median/5-year OS | Local Failure | Metastatic Disease |
---|---|---|---|---|
RTOG 9704 Regine et al. | 451 | 20.5 months/22% (gemcitabine arm) 17.2 months/18% (5-FU arm) | 28% (all patients) | 73% (all patients) |
CONKO-001 Oettle et al. | 368 | 22.1 months/23% (gemcitabine arm) 20.2 months/11.5% (observation arm) | 34% (gemcitabine) 41% (observation) | 56% (gemcitabine) 49% (observation) |
Johns Hopkins Herman et al. (9) | 271 | 21.2 months/20.1% | Not reported | |
Mayo Clinic Miller et al. (10) | 269 | 25.2 months/28% | Not reported |
Abbreviations: OS = overall survival; RTOG = Radiation Therapy Oncology Group.