Table 1.
Expression of retinoblastoma protein (pRB) in normal cervical squamous epithelium, cervical intraepithelial neoplasia and invasive carcinoma of the uterine cervix.
| Histological type | Total | % of pRB immunostaining | ||||
|---|---|---|---|---|---|---|
| 0 (0%) | +1 (1–24%) | +2 (25–49%) | +3 (50–74%) | +4 (75–100%) | ||
| Normal | 0 | 0 | 0 | 8/10(80%) | 2/10(20%) | 0 |
| Cervical intraepithelial neoplasia (CIN) # | ||||||
| CIN I ** | 16 | 0 | 0 | 7/16(43.7%) | 9/16(56.3%) | 0 |
| CIN II ** | 13 | 0 | 0 | 3/13(23.3%) | 9/13(69.3%) | 1/13(7.7%) |
| CIN III ** | 14 | 0 | 0 | 1/14(7.1%) | 9/14(64.3%) | 4/14(28.6%) |
| Invasive carcinoma # | ||||||
| Squamous cell carcinoma | ||||||
| Well differentiated * | 11 | 0 | 0 | 2/11(18.2%) | 3/11(27.3%) | 6/11(54.5%) |
| Moderately differentiated ## | 28 | 0 | 1/28(3.6%) | 9/28(32.1%)) | 18/28(64.3%) | 0 |
| Poorly differentiated *## | 14 | 0 | 9/14(64.3%) | 4/14(28.6%) | 1/14(7.1%) | 0 |
| Adenocarcinoma | 11 | 0 | 0 | 4/11(36.4%) | 4/11(36.4%) | 3/11(27.2%) |
| Small cell carcinoma | 1 | 1/1 (100.0%) | 0 | 0 | 0 | 0 |
#
P>0.05
*
P<0.01
##
P<0.01
**
P>0.05