Table 5.
Seroprotective rates and GMTs for anti-HBs antibodies from Months 0 to 20 (ATP Cohort for Immunogenicity)
|
Group |
Timing |
N |
Seroprotected |
GMT (mIU/mL) |
|||||
|---|---|---|---|---|---|---|---|---|---|
| n | % | 95% CI | Value | 95% CI | |||||
| RTS,S/AS02D |
SCREENING |
115 |
44 |
38.3 |
29.4 |
47.8 |
14.5 |
10.9 |
19.2 |
| |
Post Dose 2 (Month 2) |
148 |
140 |
94.6 |
89.6 |
97.6 |
110.9 |
89.1 |
138.1 |
| |
Post Dose 3 (Month 3) |
140 |
140 |
100 |
97.4 |
100 |
667.3 |
532.9 |
835.7 |
| |
Post Dose 3 (Month 20) |
131 |
131 |
100 |
97.2 |
100 |
1520.6 |
1206.8 |
1915.8 |
| Hepatitis B |
SCREENING |
131 |
45 |
34.4 |
26.3 |
43.1 |
13.3 |
10.0 |
17.6 |
| vaccine |
Post Dose 2 (Month 2) |
147 |
82 |
55.8 |
47.4 |
64.0 |
17.1 |
13.6 |
21.4 |
| |
Post Dose 3 (Month 3) |
141 |
133 |
94.3 |
89.1 |
97.5 |
113.8 |
91.3 |
141.8 |
| Post Dose 3 (Month 20) | 132 | 129 | 97.7 | 93.5 | 99.5 | 184.3 | 144.4 | 235.4 | |
Seroprotected ≥ 10 mIU/mL.
N = number of subjects with available results.
n/% = number/percentage of subjects with titre within the specified range.