Table 1.

Parameters and variables

Parameter name	Value in simulations	Variable name	Quantity measured
nPfEMP1	300-1000	tasexual	Time remaining in current asexual cycle
nminor	20-100	Ni	Number of IRBCs of type i
nMSP	4-100	Xi	Density of IRBCs of type i per μL
X50,innate	1000/μL	Ycapacity,f(i)	Non-dimensional capacity to mount antibody response to variant f(i)
τinnate	0.5 days	Yantibody,f(i)	Non-dimensional antibody response to variant f(i)
kfever	2 C	Yinnate	Non-dimensional level of inflammatory cytokines
X50,antibody	10/μL	Yfever	Fever in degrees C
τcapacity	10 days	YMSP,j	Adaptive immune response to MSP variant j
kantibodymin	0.01	Ni+j,i	Number of IRBCs of type i with progeny expressing type i + j
kminormod	0.5	ZMS	Success probability of merozoite invasion
Cinnate	0.2	Ngametocytes,i	Number of gametocytes of stage i
Cantibody	1.5	Xgametocytes,mature	Mature female gametocytes per μL
cminormod	0.3	Pkill,i	Probability of clearing IRBC of type i
τabdecay	20 days	Pinfect	Probability of successfully infecting mosquito
Ymemory	Varies up to 0.3
KMSP	0.02
Kantigen	5e-9
nantigenswitch	7
kgametocyte	0.1
Cmerozoite	0.5
NIRBCmerozoites	16
Tasexual	2 days
Zsuccess	0.01
Ygam,50	0.05