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. 2013 Jan 28;8(1):e55018. doi: 10.1371/journal.pone.0055018

Figure 1. MIF, sTM and PC concentrations are increased in plasma of patients with DHF.

Figure 1

Levels of (A) MIF, (B) soluble thrombomodulin (sTM) and (C) Protein C (PC) in patients infected with dengue virus and in control groups. Sera from healthy controls (N, n = 12), dengue fever (DF) patients (n = 12) and dengue hemorrhagic fever patients (DHF) sorted into grades I–II (n = 28) and grades III–IV (n = 9) were assayed for MIF, sTM and PC. The amounts of MIF, sTM and PC in dengue patients were measured using ELISA kits as described in the Materials and Methods. *p<0.1, **p<0.01 and ***p<0.001 compared with corresponding values from normal controls (N). Levels of MIF and sTM were higher than in normal controls, but PC was lower than in the control.