Figure 2. Albumin exposure increases cell death in podocytes.

A, Cell death was measured using the trypan blue exclusion assay after treatment of podocytes with increasing doses of recombinant low-endotoxin human albumin (closed bars) or dextran of an equivalent molecular weight to albumin (open bars) for 24 hrs. * denotes P = 0.0003 compared to corresponding dextran-treated cells. B, Cell death after treatment of podocytes with increasing doses of human albumin (closed bars) or dextran (open bars) for 48 hrs. * denotes P<0.0001 compared to corresponding dextran-treated cells.