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. 2013 Feb;141(2):229–241. doi: 10.1085/jgp.201210870

Table 2.

Steady-state inactivation properties for hERG channels with N-terminal region deletions

Construct V1/2 k n
mV
hERG −68.69 ± 2.24 19.51 ± 0.50 9
hERG ΔN −59.60 ± 0.73a 25.72 ± 0.32b 8
hERG ΔN + N1–135 −74.15 ± 1.67 19.51 ± 0.34 10
hERG Δeag −60.97 ± 1.65a 24.74 ± 0.56b 9
hERG Δeag + N1–135 −69.71 ± 1.70 20.35 ± 0.37 9
hERG ΔN + N1–354 −68.68 ± 2.35 20.49 ± 0.64 10

Boltzmann fit values for V1/2 and slope (k). Values shown are the mean ± SEM; n indicates the number of cells.

a

P < 0.05 versus HERG WT (ANOVA).

b

P < 0.01 versus HERG WT (ANOVA).