Table 1.
Baseline Characteristics of Patients in Clinical Trial Phases 2 and 3
Phase 2 | Phase 3 | Phase 3 | |
---|---|---|---|
CAMMS 223* | CARE-MS I | CARE-MS II* | |
N = 333 | N = 581 | N = 637 | |
Mean age in years (SD) | 32.3 (8.5) | 33.0 (8.2) | 35.1 (8.6) |
Gender (% Female) | 64.3 | 64.7 | 66.9 |
Mean EDSS score (SD) | 2.0 (0.7) | 2.0 (0.8) | 2.7 (1.2) |
Median disease duration in years (range) | 1.3 (0.1-6.3) | 1.7 (0.1-6.0) | 3.8 (0.2-16.9) |
Mean no. relapses in past 2 years (range) | 2.3 (1-7) | 2.4 (1-7) | 2.7 (1-9) |
CAMMS = Campath in Multiple Sclerosis; EDDS = Expanded Disability Status Scale; MS = Multiple Sclerosis
*Only including patients on the 12 mg/kg alemtuzumab arm