Fig. 10.

Schematic representation of the pathways arising from the dorsal subdivision of the thalamic midline nuclei (green), medial prefrontal cortex (mPFC, light blue) or caudal portion of the basal nucleus of the amygdala (BA, red) by means of anterograde tracing, and targeting: pyramidal neurons (Py) and interneurons expressing mGlu1α receptors (I) in the BA; or medium-spiny (s) and large (L) mGlu1α+ neurons in the ITCs. The size of the inputs is roughly proportional to their relative density. The selective presence of presynaptic mGlu7a receptors at specific pathways is shown by a light brown contour (as indicated by arrows). The respective frequency of asymmetric synapses on spines or dendrites as well as symmetric synapses formed by presynaptic axon terminals containing mGlu7a or mGlu8a receptors in the ITCs (upper pie diagrams) and BA (lower pie diagrams) is also shown.