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. Author manuscript; available in PMC: 2013 Jun 4.
Published in final edited form as: Mol Pharm. 2012 May 3;9(6):1841–1846. doi: 10.1021/mp300138n

Figure 3. Hsp90α levels directly affect hERG trafficking efficiency.

Figure 3

Western blot analysis of cell lystates from HEK-hERG cells that either express Hsp90α or Hsp90β targeted shRNA after doxycyline treatment for (A) 24 h. or (B) 48 h. treatment. C) and D) Densitometry analysis of Western blots from A and B (Hsp90α knockdown) respectively. E) and F) Densitometry analysis of Western blots from A and B (Hsp90β knockdown) respectively. Western blot analysis of cell lystates from HEK-hERG cells expressing G) Hsp90α targeted shRNA or H) Hsp90β targeted shRNA after 48 h. doxycycline treatment.