Table 2.
Clinical correlates of sST2.
| Covariates included in the modela | Regression coefficientb | SE | P |
|---|---|---|---|
| General sample | |||
| All | |||
| Female sex | −0.206 | 0.013 | <0.001 |
| Age, per 10 years | 0.027 | 0.007 | <0.001 |
| BMI, per 5.2 kg/m2 | 0.011 | 0.007 | 0.09 |
| Systolic blood pressure, per 19 mmHg | 0.019 | 0.007 | 0.006 |
| Use of antihypertensives | 0.032 | 0.017 | 0.03 |
| Diabetes | 0.104 | 0.020 | <0.001 |
| Men | |||
| Age, per 10 years | 0.010 | 0.010 | 0.35 |
| BMI, per 5.7 kg/m2 | −0.015 | 0.011 | 0.20 |
| Systolic blood pressure, per 21 mmHg | 0.031 | 0.011 | 0.005 |
| Use of antihypertensives | 0.024 | 0.022 | 0.27 |
| Diabetes | 0.121 | 0.030 | <0.001 |
| Women | |||
| Age, per 10 year | 0.042 | 0.009 | <0.001 |
| BMI, per 4.4 kg/m2 | 0.024 | 0.008 | 0.002 |
| Systolic blood pressure, per 17.0 mmHg | 0.009 | 0.009 | 0.31 |
| Use of antihypertensives | 0.043 | 0.020 | 0.03 |
| Diabetes | 0.091 | 0.029 | 0.002 |
| Reference sample | |||
| All | |||
| Female sex | −0.233 | 0.038 | <0.001 |
| Age, per 8.9 years | 0.029 | 0.010 | 0.006 |
| BMI, per 2.8 kg/m2 | −0.020 | 0.011 | 0.07 |
| Men | |||
| Age, per 8.9 years | 0.029 | 0.016 | 0.07 |
| BMI, per 2.4 kg/m2 | −0.023 | 0.019 | 0.22 |
| Women | |||
| Age, per 9 years | 0.026 | 0.014 | 0.06 |
| BMI, per 2.8 kg/m2 | −0.019 | 0.013 | 0.15 |
For the reference sample, covariates in the model included age, sex, BMI, systolic blood pressure, smoking status, and total and HDL cholesterol. For the general sample, covariates in the model included age, sex, BMI, systolic blood pressure, use of an antihypertensive medication, smoking status, total and HDL cholesterol, LV hypertrophy (by ECG), diabetes, and atrial fibrillation.
Regression coefficients represent expected increment in log(sST2) for presence vs absence (or 1 SD increment) of the categorical (or continuous) covariates shown.