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(a) Pre-ion/ion reaction nano-ESI spectrum of α-synuclein. (b) Post-transmission mode ion/ion reaction (using PDCH anions) mass spectrum of α-synuclein using a high amplitude supplementary AC signal applied to an opposing pair of ion trap electrodes to inhibit reactions of the lower charge states. Reprinted from ref. 59, “Charge state dependent fragmentation of gaseous α-synuclein cations via ion trap and beam-type collisional activation,” Copyright 2009, with permission from Elsevier.
