Table 12.
Choice of drug therapy in patients with comorbid conditions - drugs that may have unfavorable effect on comorbid conditions
| Conditions | Drug |
|---|---|
| Bronchospasm | β Blockers |
| Bilateral renal vascular disease | ACEI, ARB |
| Depression | Central α-agonists (Reserpine) |
| Diabetes type I and II | β-blockers, high dose diuretics |
| Heart block 2° or 3° | Β-blockers and non-DHP CCBs |
| Heart failure | CCBs (except long acting DHP) |
| Hyperkalemia | ACEI, ARB, aldosterone blockers |
| Gout | Hydrochlorothiazide |
| Liver disease | Labetalol, methyldopa |
| Peripheral vascular disease | β-blockers |
| Pregnancy | ACEI,* ARB* |
| Renal insufficiency | Potassium sparing agents, aldosterone blockers |
*
Contraindicated
ACEI: Angiotensin-converting enzyme inhibitors, ARB: Angiotensin receptor blockers, CCB: Calcium channel blockers, DHP: Dihydropyridine