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. Author manuscript; available in PMC: 2014 Feb 1.
Published in final edited form as: Biochimie. 2012 Nov 3;95(2):419–428. doi: 10.1016/j.biochi.2012.10.018

Table 2.

Inhibition of the NmAPN by selected organophosphorus compounds, derivatives of arginine (1) and homophenylalanine (2–6).

Inhibitor IC50 [μM] Ki [μM]
1, ArgP 1.91 ± 0.18 1.46 ± 0.14
2, hPheP 1.66 ± 0.07 1.26 ± 0.05
3, hPhePH 1.91 ± 0.05 1.45 ± 0.04
4, hPheP(CH2)Phe 0.397 ± 0.024 0.302 ± 0.018
5, hPheP(CH2)Tyr 0.070 ± 0.007 0.054 ± 0.005
6, hPheP(CH2NH)Tyr 3.29 ± 0.15 2.51 ± 0.11