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Criteria used to diagnose the vascular of EDS.
| Major criteria (2 or more highly indicative) |
| Arterial rupture or intestinal, uterine rupture |
| Extensive bruising |
| Thin, translucent skin |
| Characteristic facial appearance |
|
|
| Minor criteria |
| Acrogeria |
| Hypermobility of small joints (fingers) |
| Tendon and muscle rupture |
| Clubfoot |
| Varicose veins of early onset |
| Arteriovenous malformation |
| Carotid-cavernous sinus fistula |
| Pneumothorax or hemothorax |
| Positive family history of sudden death |
