Table 3.

Pre-Treament to Post-Treatment Decrease Social Anxiety Severity and Change in Brain Activation: Whole-brain Voxel-wise Regression^a

		MINI Coordinates			Volume
	Region	x	y	z	(mm3)	Z
Fearful > Happy
Positive Correlation	Middle Occipital Gyrus	−34	−92	22	1208	3.11
(decreasing activation)
Negative Correlation	Postcentral Gyrus	44	−30	54	1224	3.28
(increasing activation)	Superior Frontal Gyrus	−14	32	32	200	2.92
	Mid Cingulate	−4	−28	46	216	2.67
Angry > Happy
Positive Correlation	Precuneus	−10	−78	52	7904	4.46
(decreasing activation)	Superior Occipital Gyrus	24	−80	44	2512	3.80
	Middle Occipital Gyrus	36	−76	12	1336	3.79
	Fusiform Gyrus	−26	−2	−48	448	3.62
	Superior Frontal Gyrus	−20	14	64	216	3.34
	Superior Parietal Gyrus	−22	−52	50	672	3.28
	Lingual Gyrus	16	−76	−14	192	2.94
Negative Correlation	Superior Frontal Gyrus	−10	30	64	272	3.02
(increasing activation)

^aAll listed clusters significant at p<0 .005 (uncorrected) with a cluster extent threshold of greater than 20 contiguous voxels. Areas showing a priori hypothesized treatment-related changes are bolded and italicized, significant at p<0 .05 (SVC-corrected for multiple comparisons).

^bMedial Orbital Gyrus is referred to as ventral medial prefrontal cortex in the text. MNI, Montreal Neurological Institute; Z, Z-score.