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. Author manuscript; available in PMC: 2014 Mar 1.
Published in final edited form as: Biochim Biophys Acta. 2012 Dec 20;1832(3):391–399. doi: 10.1016/j.bbadis.2012.12.005

Figure 7. IGF-1 prevented oxidative stress induced premature cell senescence.

Figure 7

hAECs were exposed to 100 ng/mL IGF-1 for 24 hr, subsequently exposed to 100 µM hydrogen peroxide for 1 hr. Cells were replated and cultured to sub-confluence. Cell number positive for senescence-associated β-galactosidase expression was counted using Image J software. IGF-1 suppressed hydrogen peroxide-induced β-galactosidase expression (P<0.05, n=3). The data represents 3 independent experiments.