Table 2.
Comparison of different studies that have measured TL in human buccal cells
| Reference | N (male/female) | Age in years | Method | Study outcome | Telomere lengtha |
|---|---|---|---|---|---|
| Shalev et al. (2012) [33] |
236 Children (120/116) | 5 (baseline) 10 (follow-up) |
T/S ratio | Exposure to violence | 1.08 (SD = 0.44) range 0.02–3.07 0.96 (SD = 0.28) range 0.06–1.71 |
| Wong et al. (2011) [107] |
27 Cases (23/4) 24 Controls (20/4) 29 Case’s offspring (17/12) 25 Control’s offspring (9/16) |
69 (+/−6.9) 66 (+/−6.6) 40 (+/−6.8) 38 (+/−6.0) |
T/S ratio | Ischemic heart failure | 0.97 (SD = 0.27) 1.04 (SD = 0.19) 1.17 (SD = 0.42) 1.21 (SD = 0.25) |
| Kroenke et al. (2011) [50] |
78 Children (31/47) | 5 to 6 | T/S ratio | Laboratory-based stress challenge |
0.97 (SD = 0.26) range 0.33–1.59 |
| Drury et al. (2011) [32] |
100 Children (59/41) | 6 to 8 8 to 9 9 to 10 |
T/S ratio (modified) |
Social deprivation | Median 9.5 (SD = 6.4) Median 8.8 (SD = 6.0) Median 10.0 (SD = 6.5) |
| Gadalla et al. (2010) [74] |
21 Patients (IBMFS) (15/6) | 21 range 8–43 |
T/S ratio | Comparative tissue analysis |
Median 1.16 range 0.51–6.44 |
| Hewakapuge et al. (2008) [64] |
167 Individuals (71/96) | 1 to 96 | T/S ratio | Age prediction | range 0.54–2.83 (SD = 0.51) |
| Thomas et al. (2008) [108] |
30 Young controls (15/15) 26 Adult controls (11/15) 23 Young cases (8/15) 31 Adult cases (8/23) |
22.5 (+/−2.2) 68.7 (+/−2.6) 70.7 (+/−4.1) 83.1 (+/−4.5) |
T/S ratio (modified) |
Alzheimer’s disease | 41.98 (SD = 32.66) 40.57 (SD = 19.28) 34.41 (SD = 34.05) 20.51 (SD = 18.04) |
| Broberg et al. (2005) [109] |
63 Cases (54/9) 158 Controls (121/37) |
Median 69 range 35–85 Median 68 range 21–90 |
T/S ratio | Bladder cancer | Median 0.95 range 0.53–3.2 Median 1.1 range 0.51–2.4 |