FIG. 3.

Chronic OR-PAM and OCT coregistered images showing the development of neovasculature in the same scaffold as in Figure 2. (A–C) Coregistered 3D depictions of the vasculature (red) and scaffold/tissue construct (green) at 2, 4, and 6 weeks postimplantation, respectively. The arrowheads indicate the growth of neovasculature into the pores of the scaffold (scale bars: 500 μm). (D–F) Coregistered B-scan images at the planes indicated by dotted lines in (A–C), respectively, showing the gradual inward growth of blood vessels into the inner pores of the scaffold. The signals from the skin layer were removed from all the OCT images to clearly show the boundaries between the blood vessels outside and inside the scaffold. Color images available online at www.liebertpub.com/tec