Table 1. Influence of Substituent at the 3-Position of Pyridine on the Direct Arylation Process^a.

entry	reactant 4	R	product 5	convb (%)	yieldc (%)
1	1a	H	3a	9	ni
2	4b	Cl	5b	10	ni
3	4a	CH3	5a	85	64
4	4c	CF3	5c	90	78
5	4d	Ph	5d	100	90

^aReaction conditions: 4 (0.5 mmol), 6a (0.75 mmol), Ru₃(CO)₁₂ (5 mol %), and pinacolone (0.5 mL).

^bConversion based on GC analysis with respect to 4 (dodecane as internal standard).

^cni = not isolated.