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. 2012 Dec 13;78(2):658–672. doi: 10.1021/jo302547q

Table 4. Direct Arylation of N-Substituted Benzylic Aminesa.

graphic file with name jo-2012-02547q_0017.jpg

entry starting material R1 R2 convb (%)
1 1a H H 9
2 4a Me H 86
3 17 H Me 8
4 18 Me Me 17
a

Reaction conditions: Benzylic amine (0.5 mmol), 6a (0.75 mmol), Ru3(CO)12 (5 mol %), and pinacolone (0.5 mL).

b

Conversion determined by GC analysis with respect to benzylic amine.