. 2012 Jul 26;134(31):12943–12946. doi: 10.1021/ja3068269

Table 5. Scope of the Cross-Conjugated Trienamine Asymmetric γ′-Addition of 2,4-Dienals 1 with Vinyl Bis-sulfones 10^a.

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ent	R¹	R²	yield^b (%)	dr^c	ee^d (%)
1	OTBDMS	H	11a (73)	–	93
2	OTBDMS	Ph	11b (41)	2:1	99
3	Me	Ph	11c (48)	3:1	99

See SI.

Yields refer to the diastereomerically pure products 11 isolated by FC.

Determined by ¹H NMR of the crude mixture.

Determined by chiral stationary phase UPC².

Table 5. Scope of the Cross-Conjugated Trienamine Asymmetric γ′-Addition of 2,4-Dienals 1 with Vinyl Bis-sulfones 10a.