Figure 11.

Score plot derived from PCA using four descriptors (E_i, E_ea, E_eas, and H_don), applied for modeling the cytotoxicity in SW480 cells (model 3): cluster I, compounds with a terminal free CH₂OH group in the axial ligands; cluster II, amides and free carboxylic acids from subset 1; cluster III, amides and free carboxylic acids from subset 2 and 17 and 18 from subset 1; cluster IV, esters from subset 1 (without the EtNH₂ derivatives); cluster V, esters from subset 1/the EtNH₂ derivatives; cluster VI, esters from subset 2.