Table 4. Significance of the Descriptors (as Single Parameters), Based on the Properties–Biological Response Correlationa.
| correlation with the response | CH1 cells | SW480 cells |
|---|---|---|
| strong (R > |0.5|) | Hacc, q(Pt), Eeas′, Hdon, Eeas | Hacc, q(Pt), Eeas |
| middle (R < |0.5|) | COOH, Es′, Es, Eea | Hdon, Eeas′ |
| weak (R < |0.3|) | EHOMO, MW, Ei, H/Lgap, Eis | Es′, Es, COOH, MW, EHOMO, Eea, ELUMO, Eis, Vm, Ei |
| very weak (R < |0.15|) | Vm, α, μ, SASA, ELUMO | α, μ, SASA, H/Lgap |
a
for the abbreviations see the experimental section.