Table 1.
Mean EFR50, 1/α and Q0 values (± SEM) obtained for methadone (0.032 mg/kg/inj) available alone or in combination with various proportions of the delta-opioid agonist SNC80
| Self-administered solution | EFR50 | 1/α | Q0 |
|---|---|---|---|
| Methadone alone | 31 (±11) | 39,440 (±5,690) | 93 (±23) |
| 0.1:1 SNC80/methadone | 36 (±14) | 43,760 (±14,511) | 82 (±12) |
| 0.3:1 SNC80/methadone | 29 (±10) | 51,535 (±6,144) | 68 (±13) |
| 0.9:1 SNC80/methadone | 29 (±10) | 57,641 (±13,013) | 87 (±7) |
| ANOVAs |
F(3,9)=0.13 p>0.05 |
F(3,9)=1.02 p>0.05 |
F(3,9)=1.48 p>0.05 |
ANOVA results for effect of self-administered solution on EFR50, 1/α and Q0 values are shown in the bottom row