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. Author manuscript; available in PMC: 2014 Jan 9.
Published in final edited form as: J Am Chem Soc. 2012 Dec 21;135(1):354–366. doi: 10.1021/ja3095558

Scheme 1. Experimental systems for non-enzymatic extension.

Scheme 1

(A) DNA template and primer; (B) RNA template, DNA primer. All primer sequences contain a 3′-amino-2′,3′- dideoxynucleotide as the 3′ terminal nucleotide.