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. 2013 Jan;19(1):115–118. doi: 10.3201/eid1901.121007

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This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.

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Phylogenetic relationships among genotypes 1–4, wild boar, rabbit, avian (bird), and rat hepatitis E virus (HEV) isolates. The nucleic acid sequence alignment was performed by using ClustalX 1.81 (www.clustal.org). The genetic distance was calculated by the Kimura 2-parameter method. A phylogenetic tree with 1,000 bootstrap replicates was generated by the neighbor-joining method, based on the entire genome (A) and open reading frame 3 (B) of the genotypes 1–4, wild boar, rabbit, chicken (avian), and rat HEV isolates. Scale bar indicates nucleotide substitutions per site. Boldface indicates isolates used in this study.