. Author manuscript; available in PMC: 2013 Jan 29.

Published in final edited form as: Neuropsychopharmacology. 2009 Jun 3;34(10):2252–2264. doi: 10.1038/npp.2009.52

Table 2.

Top Ranked SNPs Associated with the FTND in the Treatment Seeking Smoker Cohort

SNP	Gene	Genomic¹	Major²	Minor³	MAF⁴	Model⁵	Beta⁶	SE⁷	P_LRT⁸	P_ACT⁹
rs10891552	DRD2	IVS1+12127	A	T	0.04	Add	0.87	0.27	0.0014	0.037
rs2975226	SLC6A3	−2303	T	A	0.39	Add	0.31	0.10	0.0029	0.057
rs2652510	SLC6A3	−4547	T	C	0.40	Dom	0.45	0.15	0.0026	0.081
rs834829	NR4A2	−14150	G	A	0.29	Dom	0.37	0.15	0.0117	0.091
rs2652511	SLC6A3	−3076	G	A	0.39	Dom	0.44	0.15	0.0033	0.097

Genomic, location of SNP relative to gene.

Major, major or referent allele.

Minor or variant allele.

⁴

MAF, minor allele frequency.

⁵

Models are Additive (Add) and Dominant (Dom).

⁶

Coefficient of genotype term of GLM model. A positive value implies association of the minor allele with increased FTND.

⁷

SE, standard error of Beta.

⁸

Likelihood ratio test P value.

⁹

P value adjusted for correlated tests.