Table 5.

FBAT of the FTND in the Multiplex Ever Smoker Pedigree Cohort

SNP	Gene	Modell	Frequency2	Pedigrees3	Z4	PFBAT5
rs10891552	DRD2	A/D & G	0.11 & 0.21	15	2.301	0.0214
rs2975226	SLC6A3	G	0.17	42	3.065	0.0022
rs2652510	SLC6A3	G	0.11	47	3.059	0.0022
rs834829	NR4A2	G	0.32	67	1.951	0.0511
rs2652511	SLC6A3	G	0.10	42	2.856	0.0043

¹FBAT genetic model: A=Additive, D=Dominant, G=Genotype;

²allele or genotype frequency of minor allele model tested;

³number of informative pedigrees;

⁴normalized Z score, (S-E(S))/Var(S)), where a positive Z implies association of the genotype with a higher FTND score;

⁵P value of FBAT.