Etiology |
Mycobacterium bovis, used as an intravesical treatment for urothelial cancer of the bladder |
Incidence |
0.4% of patient treated with intravesical BCG |
Gender Ratio |
Male only |
Age predilection |
Generally, men older then 60 years old |
Risk factors |
Intravesical treatment with BCG, recent instrumentation or catheterization, immunocompromised state, recent urological trauma |
Treatment |
300 mg of isoniazid for 3 months supplemented with rifampin and isonicotinylhydrazine (INH) with or without fluoroquinolones for 3–6 months +/− corticosteroids |
Prognosis |
Orchiectomy can be avoided if promptly diagnosed and treated |
Ultrasonography |
Variable. Classically, diffuse enlargement with heterogeneous hypoechoic appearance of the epididymis, nodular enlargement of the testis with heterogeneous hypoechoic appearance, linear or focal Doppler signal at the periphery of the epididymis, intra-scrotal extra-testicular calcifications, caseous abscess, sinus tract and skin thickening |