A 3-year-old girl suffered from merosin-deficient congenital muscular dystrophy (MDCMD). Apparent Diffusion Coefficient (ADC) mapping reveals abnormally high free-water concentrations in periventricular white matter, especially at bilateral occipital regions. (Protocol: Magnet strength 1.5, TR 10000, TE 81.6/FE, without contrast, 5 mm slice thickness)