Table 6.
Distribution of the tumors within the immunohistochemistry intrinsic classes according to SBR grade and array CGH-based genomic characteristics
| All n = 135 (%) | Luminal A n = 83 | Luminal B n = 33 | HER2-enriched n = 10 | Basal n = 7 | Unclassified n = 2 | |
|---|---|---|---|---|---|---|
| SBR Grade | ||||||
| 1 |
25 (18) |
24 (29) |
0 |
0 |
1 (14) |
0 |
| 2 |
71 (53) |
53 (64) |
16 (49) |
1 (10) |
0 |
1 |
| 3 |
39 (29) |
6 ( 7) |
17 (52) |
9 (90) |
6 (86) |
1 |
| Array CGH clusters | ||||||
| a |
34 (25) |
17 (20) |
5 (15) |
5 (50) |
6 (86) |
1 |
| b |
25 (18) |
20 (24) |
3 ( 9) |
2 (20) |
0 |
0 |
| c |
16 (12) |
7 ( 8) |
8 (24) |
0 |
0 |
1 |
| d |
13 (10) |
9 (11) |
3 ( 9) |
1 (10) |
0 |
0 |
| e |
35 (26) |
23 (28) |
11 (33) |
1 (10) |
0 |
0 |
| f |
12 ( 9) |
7 ( 8) |
3 ( 9) |
1 (10) |
1 (14) |
0 |
| Nb. of amplicons | ||||||
| 0 |
71 (53) |
56 (67) |
7 (21) |
1 (10) |
6 (86) |
1 |
| ≥1 |
64 (47) |
27 (33) |
26 (79) |
9 (90) |
1 (14) |
1 |
| Range |
1–17 |
1–10 |
1–17 |
1–11 |
NA |
1 |
| Mean |
4.9 |
3.6 |
5.6 |
4.9 |
9 |
1 |
| G2I classes | ||||||
| 1 |
19 (14) |
16 (19) |
2 ( 6) |
1 (10) |
0 |
0 |
| 2 |
88 (65) |
55 (66) |
19 (58) |
6 (60) |
6 (86) |
2 |
| 3 | 28 (21) | 12 (15) | 12 (36) | 3 (30) | 1 (14) | 0 |