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. 2013 Jan 14;8:11. doi: 10.1186/1750-1172-8-11

Figure 4.

Figure 4

Few F508del-CFTR correctors correct the trafficking of hERG F805C. (A) A representative immunoblot is shown for cells transfected with vector control (vector), wt hERG (wt), and hERG F805C treated with negative control (DMSO), positive control (DMSO 29°C), astemizole, VRT-325, decreasing concentrations of KM60, KM57, and ouabain (ouab). Arrows indicate core and complex-glycosylated hERG F805C. Tubulin is shown as a loading control. (B) A representative immunoblot is shown for cells transfected with vector control (vector), wt hERG (wt), and hERG F805C treated with negative control (DMSO), positive control (DMSO 29°C), astemizole, VRT-325, decreasing concentrations of RDR1 and glafenine. Arrows indicate core and complex-glycosylated hERG F805C. Tubulin is shown as a loading control.