Table 3.
Change in FVC, FEV1, and FEF25-75 FEF1/FVC post-bronchodilator by ADRB2 haplotype1
| |
Arg16Gly/Gln27Glu GG haplotype group |
p- value |
||
|---|---|---|---|---|
| 0 GG (n = 56) | 1 GG (n = 34) | 2 GG (n = 4) | ||
| Change in FVC(%) |
-0.17 ± 9.86 |
2.29 ± 11.87 |
5.25 ± 4.03 |
0.17 |
| Change in FEV1(%) |
2.10 ± 9.42 |
2.18 ± 9.57 |
2.75 ± 11.41 |
0.92 |
| Change in FEV1/FVC(%) |
4.61 ± 10.45 |
0.53 ± 7.75 |
-2.25 ± 9.61 |
0.02 |
| Change FEF25-75(%) | 6.36 ± 30.75 | 8.62 ± 41.75 | 8 ± 39.45 | 0.79 |
% - Percentage; FVC - forced vital capacity; FEV - forced expiratory volume; FEF25-75% - forced expiratory flow between 27-75% of the FVC. Statistical analysis performed by linear regression. 1. Percent change calculated as 100 x (post-bronchodilator value – pre-bronchodilator value)/pre-bronchodilator value.