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. 2013 Jan 29;8(1):e53106. doi: 10.1371/journal.pone.0053106

Figure 1. Sirt1 expression is reduced in patients suffering from atherosclerotic disease. A.

Figure 1

HDL levels are reduced in patients suffering from CAD or ACS as compared to the healthy controls. B. Flow cytometry analysis demonstrates the purity of isolated monocytes. C. Sirt1 mRNA expression in relation to 18S rRNA in peripheral blood monocytes isolated from healthy subjects, from patients with angiographically-confirmed CAD and patients presenting with an ACS. D. The expression of interleukin-6 (IL-6), a negatively regulated Sirt1-dependent marker, is increased in patients with impaired Sirt1-expression.