Table 3.
Cross-sectional associations between intake of 100 μg of dietary phylloquinone and inflammatory or metabolic markers at baseline
Change in inflammatory marker for 100 additional μg of dietary phylloquinone intake (95%confidence intervals) | P | |
---|---|---|
C-Peptide (ng/mL) |
−0.73 (−2.68 to 1.27) |
0.472 |
Ghrelin (pg/mL) |
−1.25 (−3.76 to 1.33) |
0.339 |
GIP (pg/mL) |
−0.13 (−2.98 to 2.80) |
0.928 |
GLP-1 (ng/mL) |
−1.81 (−5.40 to 1.91) |
0.335 |
IL-6 (pg/ml) |
−1.68 (−5.46 to 2.25) |
0.396 |
Leptin (ng/mL) |
−1.48 (−3.80 to 0.90) |
0.221 |
PAI-1 (ng/mL) |
−1.64 (−3.23 to −0.0)2 |
0.047 |
Resistin (ng/mL) |
−1.42 (−3.61 to 0.81) |
0.210 |
TNF (pg/mL) |
−1.24 (−5.73 to 3.46) |
0.598 |
Visfatin (ng/mL) |
−1.42 (−6.54 to 3.98) |
0.599 |
Adiponectin (μg/mL) |
2.45 (−2.23 to 7.35) |
0.310 |
Adipsin (μg/mL) | 1.21 (−2.84 to 5.43) | 0.563 |
Multivariable linear regression models were used for analysis. Data are given in % of change (95% IC). Models are adjusted for sex, age, body-mass-index, smoking (never, current, past), total energy intake (kcal/d), dietary fibre intake (g/d), dietary polyunsaturated fatty acids intake (g/d), physical activity (kcal/d), Mediterranean Diet Score (14-item PREDIMED score, quantitative), and T2DM. GIP Gastric inhibitory polypeptide, GLP-1 Glucagon-like peptide-1, IL-6 Interleukin-6, PAI-1 Plasminogen activator inhibitor-1, TNF Tumor Necrosis Factor α.