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. 2013 Jan 29;8(1):e55231. doi: 10.1371/journal.pone.0055231

Figure 4. Effect of CP-346086 or tyloxapol administration to rats on postprandial serum lipid levels at different time points.

Figure 4

Male rats were fasted overnight and administered vehicle, CP-346086 (500 µg/kg i.p.) or tyloxapol (700 mg/kg i.p.). One hour later, they were subjected to gavage with 5 ml of virgin olive oil, and serum cholesterol (A), phospholipids (B) and triglycerides (C) were determined at the indicated time points. Values are expressed as the mean and SD of 7 animals for each group. Statistical analysis to evaluate dietary response was done using one-way ANOVA and the Mann-Whitney U test as post hoc test. a, p<0.05 and A p<0.01 for MTP vs control; b, p<0.05 and B p<0.01 for tyloxapol vs control; and c p<0.05 and C p<0.01 for MTP vs tyloxapol.