Table 2. Neural correlates of working memory load.
| 2-back versus 0-back | |||||
| Region | x | y | z | SPM T | p (FWE-corr.) |
| Right ventrolateral PFC (BA 47) | 30 | 23 | −2 | 5.76 | 0.001 |
| Left dorsolateral PFC (BA 46) | −45 | 29 | 28 | 5.80 | 0.001 |
| −30 | −1 | 52 | 8.24 | 0.000 | |
| Right dorsolateral PFC (BA 6, 46) | 30 | 2 | 52 | 8.64 | 0.000 |
| 42 | 38 | 28 | 6.13 | 0.000 | |
| Left frontopolar cortex (BA 10) | −33 | 47 | 13 | 7.25 | 0.001 |
| Left premotor cortex (BA 6) | −39 | 2 | 25 | 5.55 | 0.001 |
| Left insula (BA 13) | −30 | 20 | 1 | 6.04 | 0.000 |
| Left dACC (BA 32) | −6 | 17 | 43 | 8.97 | 0.000 |
| Right dACC (BA 32) | 12 | 32 | 22 | 6.10 | 0.000 |
| Left posterior parietal cortex (BA 7, 40) | −30 | −49 | 37 | 6.65 | 0.000 |
| −9 | −67 | 49 | 8.55 | 0.000 | |
| −42 | −43 | 37 | 6.41 | 0.000 | |
| Right posterior parietal cortex (BA 7, 40) | 18 | −67 | 52 | 8.78 | 0.000 |
| 42 | −40 | 43 | 6.92 | 0.000 | |
| Left precuneus (BA 19) | −27 | −73 | 31 | 5.99 | 0.001 |
| Thalamus | 9 | −22 | 10 | 6.64 | 0.001 |
| Left cerebellum | −36 | −67 | −32 | 8.63 | 0.001 |
| Right cerebellum | 9 | −79 | −26 | 5.37 | 0.002 |
| 3 | −34 | −17 | 6.82 | 0.001 | |
| Brain stem | 6 | −28 | −8 | 7.60 | 0.001 |
| Left hypothalamus | −9 | −7 | −5 | 4.95 | 0.010 |
| Left caudate | −15 | 5 | 13 | 6.14 | 0.001 |
| Left pallidum | −12 | 2 | 1 | 5.76 | 0.001 |
| Right pallidum | 12 | −4 | 1 | 5.36 | 0.002 |
Activations related to working memory load (2-back vs. 0-back), separated by stimulus valence (neutral vs. emotional). All activations were whole-brain FWE-corrected (p<.05). Abbreviations: BA: Brodmann area; dACC: dorsal anterior cingulate cortex; PFC: prefrontal cortex.