Table 3.

Valgus and lateral JSN progression in 30 months on PA view radiograph in knees without radiographic OA at the time of the long limb film

MOST STUDY
HKA	N of knees	N (%) of lateral cartilage progression	Crude OR (95% CI)	Adjusted OR (95% CI) *	p-value
−1.1 or below-- varus	1314	6 (0.5)	0.2 (0.1, 0.6)	0.2 (0.1,0.6)	0.0019
ref: −1 to 1	1333	25 (1.9)	1.0	1.0
1.1 to 3 valgus	442	14 (3.2)	1.7 (0.9, 3.3)	1.5 (0.8,3.0)	0.2262
3.1 or above --valgus	148	8 (5.4)	2.9 (1.2, 6.7)	2.5 (1.0,5.9)	0.0406
OAI
HKA	N of knees	N (%) of lateral JSN progression	Crude OR (95% CI)	Adjusted OR (95% CI) **	p-value
−1.1 or below--varus	1454	3 (0.2)	0.5 (0.1,2.7)	0.5 (0.1,2.6)	0.3844
ref: −1 to 1	888	4 (0.5)	1.0	1.0
1.1 to 3 valgus	531	3 (0.6)	1.3 (0.3,5.6)	1.3 (0.3,5.7)	0.7641
3.1 or above --valgus	182	3 (1.7)	3.7 (0.8,16.3)	3.6 (0.9,14.8)	0.0822

^*Adjusting age, sex, BMI, and Kellgren & Lawrence grade at baseline

^**Adjusting age, sex, BMI, and Kellgren & Lawrence grade at the visit when alignment was measured