Table 5.
Valgus and lateral meniscal progression in 30 months on MRI films in the MOST Study
| Progression of either lateral meniscal tear or lateral meniscal extrusion | |||||||
|---|---|---|---|---|---|---|---|
| N of knees | N (%) of lateral cartilage progression | Crude RR (95% CI) | Adjusted RR (95% CI) * | p-value | Adjusted RR (95% CI) ** | p-value | |
| All knees | |||||||
| −1.1 or below -- varus | 933 | 25 (2.7) | 0.7 (0.4,1.2) | 0.5 (0.3,1.0) | 0.0341 | 0.5 (0.3,0.9) | 0.0245 |
| ref: −1 to 1 | 637 | 25 (3.9) | 1.0 | 1.0 | 1.0 | ||
| 1.1 to 3 valgus | 249 | 19 (7.6) | 1.9 (1.1,3.6) | 1.8 (1.0,3.2) | 0.0719 | 1.7 (0.9,3.1) | 0.0905 |
| 3.1 to 5 valgus | 74 | 7 (9.5) | 2.4 (1.1,5.3) | 2.1 (0.9,4.6) | 0.0694 | 2.1 (0.9,4.6) | 0.0771 |
| 5.1 or above -- valgus | 41 | 11 (26.8) | 6.8 (3.7,12.8) | 3.7 (1.7,8.2) | 0.0013 | 3.4 (1.6,7.5) | 0.0022 |
| Knees with baseline KL 0-1 | |||||||
| −1.1 or below --varus | 486 | 9 (1.9) | 0.6 (0.3,1.3) | 0.6 (0.3,1.3) | 0.1683 | 0.6 (0.3,1.3) | 0.1775 |
| ref: −1 to 1 | 465 | 15 (3.2) | 1.0 | 1.0 | 1.0 | ||
| 1.1 to 3 valgus | 171 | 9 (5.3) | 1.6 (0.7,3.9) | 1.5 (0.6,3.7) | 0.3426 | 1.5 (0.6,3.6) | 0.3452 |
| 3.1 or above -- valgus | 53 | 8 (15.1) | 4.7 (2.1,10.4) | 4.3 (1.9,9.7) | 0.0004 | 4.3 (1.9,9.7) | 0.0004 |
| Knees with baseline KL 2+ | |||||||
| −1.1 or below -- varus | 447 | 16 (3.6) | 0.6 (0.3,1.3) | 0.5 (0.2,1.0) | 0.0493 | 0.4 (0.2,0.9) | 0.0245 |
| ref: −1 to 1 | 172 | 10 (5.8) | 1.0 | 1.0 | 1.0 | ||
| 1.1 to 3 valgus | 78 | 10 (12.8) | 2.2 (0.9,5.3) | 2.0 (0.8,4.7) | 0.1344 | 1.7 (0.7,4.2) | 0.2365 |
| 3.1 to 5 valgus | 28 | 2 (7.1) | 1.2 (0.3,5.3) | 1.1 (0.2,4.8) | 0.9076 | 1.1 (0.2,4.8) | 0.9458 |
| 5.1 or above -- valgus | 34 | 8 (23.5) | 4.0 (1.7,9.4) | 2.4 (0.9,6.2) | 0.0762 | 2.0 (0.8,5.1) | 0.1436 |
*
Adjusting age, sex, BMI, and Kellgren & Lawrence grade at baseline
**
Adjusting age, sex, BMI, Kellgren & Lawrence grade at baseline, and history of meniscal surgery